Conjugated Estrogens/Medroxyprogesterone

Pronunciation: KON-joo-GAY-ted ES-troe-jenz/me-DROX-ee-proe-JES-ter-one
Generic Name: Conjugated Estrogens/Medroxyprogesterone
Brand Name: Examples include Premphase and Prempro

Do not use Conjugated Estrogens/Medroxyprogesterone to prevent heart disease, heart attacks, strokes, or dementia. Conjugated Estrogens/Medroxyprogesterone may increase the risk of heart disease (including heart attack), stroke, dementia, serious blood clots in the lung or leg, or breast cancer. Talk with your doctor regularly about whether you still need treatment with Conjugated Estrogens/Medroxyprogesterone.

Conjugated Estrogens/Medroxyprogesterone is used for:

Treating menopausal symptoms (eg, hot flashes, vaginal dryness). If you are only being treated for vaginal menopause symptoms, products applied locally, such as vaginal creams, tablets, or rings, should be considered before products taken by mouth or absorbed through the skin. Conjugated Estrogens/Medroxyprogesterone is also used to prevent bone loss (osteoporosis) in women at high risk.

Conjugated Estrogens/Medroxyprogesterone is a combination of estrogen and progestin hormones. It works by replacing these hormones in the body when the body does not make enough on its own.

Do NOT use Conjugated Estrogens/Medroxyprogesterone if:

• you are allergic to any ingredient in Conjugated Estrogens/Medroxyprogesterone


• you are pregnant or think you may be pregnant


• you have abnormal vaginal bleeding, an estrogen-dependent tumor, a history of blood clots, circulation problems, active/recent stroke or heart attack, or liver disease


• you have or have had breast, uterine, ovarian, or vaginal cancer; or have had a hysterectomy (removal of the uterus)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Conjugated Estrogens/Medroxyprogesterone:

Some medical conditions may interact with Conjugated Estrogens/Medroxyprogesterone. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a family history of breast cancer or have had an abnormal breast mammogram or x-ray, a noncancerous lump on the breast, or bone cancer


• if you have asthma, diabetes, seizures, dementia, migraine headaches, heart disease (eg, high blood pressure, heart attacks, heart failure), kidney disease, an underactive thyroid, lupus, pancreatitis, or abnormal calcium levels in the blood


• if you have depression, uterus problems (eg, uterine fibroids, endometriosis), cholesterol or lipid problems, gallbladder disease, excessive weight gain, or a blood disorder (eg, porphyria), or if you are significantly overweight


• if you have had high blood pressure during pregnancy or yellowing of the skin or eyes during pregnancy or with past estrogen use


• if you are scheduled for surgery or will be on bed rest


• if you smoke cigarettes or use tobacco

Some MEDICINES MAY INTERACT with Conjugated Estrogens/Medroxyprogesterone. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Aminogluthethimide, hydantoins (eg, phenytoin), or rifampin because they may decrease Conjugated Estrogens/Medroxyprogesterone's effectiveness


• Anticoagulants (eg, warfarin) because their effectiveness may be decreased or their risk of side effects may be increased by Conjugated Estrogens/Medroxyprogesterone


• Corticosteroids (eg, prednisone) or succinylcholine because the risk of their side effects may be increased by Conjugated Estrogens/Medroxyprogesterone

This may not be a complete list of all interactions that may occur. Ask your health care provider if Conjugated Estrogens/Medroxyprogesterone may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Conjugated Estrogens/Medroxyprogesterone:

Use Conjugated Estrogens/Medroxyprogesterone as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Conjugated Estrogens/Medroxyprogesterone. Talk to your pharmacist if you have questions about this information.


• Take Conjugated Estrogens/Medroxyprogesterone by mouth with food or right after a meal to prevent stomach upset.


• Conjugated Estrogens/Medroxyprogesterone works best if it is taken at the same time each day.


• Continue to take Conjugated Estrogens/Medroxyprogesterone even if you feel well. Do not miss any doses.


• If you miss a dose of Conjugated Estrogens/Medroxyprogesterone, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Conjugated Estrogens/Medroxyprogesterone.

Important safety information:

• Conjugated Estrogens/Medroxyprogesterone may cause dizziness or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Conjugated Estrogens/Medroxyprogesterone with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Conjugated Estrogens/Medroxyprogesterone may cause dark skin patches on your face (melasma). Exposure to the sun may make these patches darker. If patches develop, consult your doctor about the use of sunscreen or protective clothing when your skin is exposed to the sun, sunlamps, or tanning booths.


• Conjugated Estrogens/Medroxyprogesterone may increase the risk of stroke, heart attack, blood clots, high blood pressure, or similar problems. The risk may be greater if you smoke (especially in women older than 35 years of age).


• You should talk to your doctor about instructions for examining your own breasts, and report any lumps to your doctor immediately.


• Before you have surgery or will be confined to a chair or bed for a long period of time (eg, a long plane flight), talk to your doctor about your use of Conjugated Estrogens/Medroxyprogesterone.


• Tell your doctor or dentist that you take Conjugated Estrogens/Medroxyprogesterone before you receive any medical or dental care, emergency care, or surgery.


• Conjugated Estrogens/Medroxyprogesterone may interfere with certain lab tests. Be sure your doctors and lab personnel know that you are using Conjugated Estrogens/Medroxyprogesterone.


• Diabetes patients - Conjugated Estrogens/Medroxyprogesterone may affect your blood sugar. Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.


• Lab tests, including blood pressure monitoring and Pap smears, may be performed while you use Conjugated Estrogens/Medroxyprogesterone. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Use Conjugated Estrogens/Medroxyprogesterone with caution in the ELDERLY; they may be more sensitive to its effects.


• Conjugated Estrogens/Medroxyprogesterone should not be used in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: Do not use Conjugated Estrogens/Medroxyprogesterone if you are pregnant. If you think you may be pregnant, contact your doctor right away. Conjugated Estrogens/Medroxyprogesterone is found in breast milk. Do not breast-feed while using Conjugated Estrogens/Medroxyprogesterone.

Possible side effects of Conjugated Estrogens/Medroxyprogesterone:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Abnormal hair growth; bloating; breast tenderness or pain; changes in sleep patterns; darkening of the skin; dizziness; fatigue; hair loss; headache; irritability; increased or decreased sex drive; lightheadedness; nausea; stomach cramps; stomach upset; weight changes.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); breast lumps; calf pain or swelling; changes in vaginal bleeding (eg, spotting, breakthrough bleeding, prolonged bleeding); chest pain; faintness; leg pain; mental or mood changes (eg, severe depression, memory loss); one-sided weakness; shortness of breath; slurred speech; sudden severe headache; swelling of hands or feet; unusual vaginal discharge, itching, or odor; vision changes; vomiting; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Conjugated Estrogens/Medroxyprogesterone side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include excessive vaginal bleeding; severe nausea and vomiting.

Proper storage of Conjugated Estrogens/Medroxyprogesterone:

Store Conjugated Estrogens/Medroxyprogesterone at room temperature, between 68 and 77 degrees F (20 and 20 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Conjugated Estrogens/Medroxyprogesterone out of the reach of children and away from pets.

General information:

• If you have any questions about Conjugated Estrogens/Medroxyprogesterone, please talk with your doctor, pharmacist, or other health care provider.


• Conjugated Estrogens/Medroxyprogesterone is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Conjugated Estrogens/Medroxyprogesterone. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Conjugated Estrogens/Medroxyprogesterone resources

• Conjugated Estrogens/Medroxyprogesterone Side Effects (in more detail)
• Conjugated Estrogens/Medroxyprogesterone Use in Pregnancy & Breastfeeding
• Conjugated Estrogens/Medroxyprogesterone Drug Interactions
• Conjugated Estrogens/Medroxyprogesterone Support Group
• 6 Reviews for Conjugated Estrogens/Medroxyprogesterone - Add your own review/rating

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Hivid

Pronunciation: zal-SITE-ah-been
Generic Name: Zalcitabine
Brand Name: Hivid

Hivid may infrequently cause severe side effects, which could be fatal. Hivid can cause severe nerve problems (peripheral neuropathy), and should be used with extreme caution in those who already suffer from this disorder. It may rarely cause swelling of the pancreas (pancreatitis). Tell your doctor immediately if vomiting, stomach/abdominal pain, or persistent nausea occur, as Hivid may need to be stopped until you can be checked. Severe and sometimes fatal lactic acidosis or severe liver disease may also occur. Rarely, fatal liver failure has occurred in those with hepatitis B infection while using Hivid. Hivid should be used with caution if you have a hepatitis B infection. Tell your doctor immediately if tingling/numbness of the hands and feet, dark urine, yellowing of eyes/skin, rapid breathing, muscle aches, or unusual drowsiness occurs.

Hivid is used for:

Treating HIV infection. It is used in combination with other medicines.

Hivid in a nucleoside reverse transcriptase inhibitor. It works by blocking the growth of HIV.

Do NOT use Hivid if:

• you are allergic to any ingredient in Hivid


• you have lactic acidosis (a metabolic disorder) or certain liver problems (eg, enlarged liver, liver steatosis, abnormal liver function tests)


• you are taking lamivudine or didanosine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Hivid:

Some medical conditions may interact with Hivid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a nervous system disease (eg, peripheral neuropathy); a history of liver disease, including hepatitis B; kidney problems; diabetes; heart problems (eg, cardiomyopathy, congestive heart failure); AIDS; high triglyceride levels; or inflammation of the pancreas


• if you have had unusual weight loss, are very overweight, have certain abnormal blood levels (eg, increased serum amylase, very low CD₄ cell count), or if you regularly consume alcoholic beverages

Some MEDICINES MAY INTERACT with Hivid. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Pentamidine or zidovudine because side effects, such as increased risk of swelling or irritation of the pancreas, may occur


• Lamivudine because effectiveness of Hivid may be decreased


• Chloramphenicol, cisplatin, dapsone, disulfiram, ethionamide, glutethimide, gold-based medicines (eg, gold sodium thiomalate), other nucleoside analogs (eg, didanosine), phenytoin, ribavirin, vincristine, hydralazine, iodoquinol, isoniazid, metronidazole, or nitrofurantoin because risk of severe nerve problems may be increased


• Aminoglycosides (eg, gentamicin), amphotericin, cimetidine, magnesium or aluminum-containing antacids, or probenecid because risk of side effects or toxic effects may be increased

This may not be a complete list of all interactions that may occur. Ask your health care provider if Hivid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Hivid:

Use Hivid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Hivid on an empty stomach at least 1 hour before or 2 hours after eating.


• Hivid must be taken with other medicines that treat HIV infection to be effective.


• Do not take Hivid at the same time you take antacids containing magnesium or aluminum.


• Continue to use Hivid even if you feel well. Do not miss any doses.


• If you miss a dose of Hivid, take it as soon as you remember. If it is within 2 hours of your next dose, skip the missed dose and go back to your regular dosing schedule. It is important not to miss doses of Hivid. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Hivid.

Important safety information:

• Do not exceed the recommended dose without checking with your doctor. Exceeding the prescribed dose of Hivid may not provide additional benefits, and may increase the risk of side effects.


• When your medicine supply begins to run low, get more from your doctor or pharmacy as soon as possible. The virus may develop resistance to Hivid if you stop taking it, even for a short period of time, and may become harder to treat.


• If you experience numbness, tingling, or pain in the hands or feet, report these symptoms to your health care provider. Parents should closely watch their children for these symptoms if they are taking this medication. Inform your health care provider if your child has ever experienced any of these symptoms.


• Contact your health care provider if severe nausea, vomiting, or stomach pain occurs.


• Hivid is not a cure for HIV infection and patients may continue to acquire illnesses/infections associated with HIV infection. Remain under the care of your health care provider.


• Hivid offers no protection from the transmission of HIV to others through sexual contact or blood contamination. Use barrier forms of contraception (eg, condoms) if you are infected with HIV.


• Changes in body fat may occur while you are taking Hivid (eg, increased fat in the upper back and stomach areas, decreased fat in the arms and legs). The cause and long-term effects of these changes are unknown. Discuss the risks and benefits of therapy with your doctor, as well as the possible role of exercise to reduce this side effect.


• LAB TESTS will be performed to monitor your progress. Be sure to keep all doctor and lab appointments.


• Use an effective form of birth control while taking Hivid.


• PREGNANCY AND BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using Hivid during pregnancy. It is unknown if Hivid is excreted in breast milk. HIV-infected mothers should not breast-feed their infants because of the risk of transmitting the HIV infection or Hivid to the baby.

Possible side effects of Hivid:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; fatigue; headache; itching; loss of appetite; nausea; shift in body fat to stomach and upper back; tiredness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); convulsions; fast, shallow breathing; feeling cold; heart problems; lactic acid imbalance (slow or irregular heartbeat; dizziness; lightheadedness); liver inflammation (liver tenderness; weakness; fatigue); numbness, tingling, burning, or sharp shooting pains in arms, hands, legs, and feet; pain on swallowing; persistent or severe nausea; severe muscle pain or cramping; sores in mouth or throat; stomach pain; swelling of the hands or feet; vomiting; weakness or exhaustion.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Hivid side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org ), or emergency room immediately.

Proper storage of Hivid:

Store tablets at room temperature, 59 to 86 degrees F (15 to 30 degrees C), in a tightly-closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Hivid out of the reach of children and away from pets.

General information:

• If you have any questions about Hivid, please talk with your doctor, pharmacist, or other health care provider.


• Hivid is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Hivid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Hivid resources

• Hivid Side Effects (in more detail)
• Hivid Use in Pregnancy & Breastfeeding
• Drug Images
• Hivid Drug Interactions
• Hivid Support Group
• 0 Reviews for Hivid - Add your own review/rating

• Hivid Concise Consumer Information (Cerner Multum)


• Hivid Advanced Consumer (Micromedex) - Includes Dosage Information


• Hivid Prescribing Information (FDA)


• HIVID Monograph (AHFS DI)

Compare Hivid with other medications

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Gris-PEG Ultramicrosize Tablets

Pronunciation: GRIS-ee-oh-FUL-vin
Generic Name: Griseofulvin
Brand Name: Gris-PEG

Gris-PEG Ultramicrosize Tablets are used for:

Treating certain fungal infections (eg, ringworm) of the hair, skin, and nails. It may also be used for other conditions as determined by your doctor.

Gris-PEG Ultramicrosize Tablets are an antifungal agent. It works by making the skin more resistant to fungal growth.

Do NOT use Gris-PEG Ultramicrosize Tablets if:

• you are allergic to any ingredient in Gris-PEG Ultramicrosize Tablets


• you have liver failure or the blood disease porphyria


• you are pregnant

Contact your doctor or health care provider right away if any of these apply to you.

Before using Gris-PEG Ultramicrosize Tablets:

Some medical conditions may interact with Gris-PEG Ultramicrosize Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have had a severe allergic reaction (eg, severe rash, hives, difficulty breathing, dizziness) to a penicillin antibiotic (eg, amoxicillin)


• if you have liver disease or lupus

Some MEDICINES MAY INTERACT with Gris-PEG Ultramicrosize Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Barbiturates (eg, phenobarbital) because they may decrease Gris-PEG Ultramicrosize Tablets's effectiveness


• Anticoagulants (eg, warfarin), cabazitaxel, cyclosporine, oral contraceptives (birth control pills), or ulipristal because their effectiveness may be decreased by Gris-PEG Ultramicrosize Tablets

This may not be a complete list of all interactions that may occur. Ask your health care provider if Gris-PEG Ultramicrosize Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Gris-PEG Ultramicrosize Tablets:

Use Gris-PEG Ultramicrosize Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Gris-PEG Ultramicrosize Tablets by mouth with or without food.


• Swallow Gris-PEG Ultramicrosize Tablets whole.


• You may also crush Gris-PEG Ultramicrosize Tablets and sprinkle it onto 1 tablespoonful of applesauce. Mix the medicine with the applesauce and swallow the mixture right away without chewing.


• To clear up your infection completely, take Gris-PEG Ultramicrosize Tablets for the full course of treatment. Keep taking it even if you feel better in a few days.


• If you miss a dose of Gris-PEG Ultramicrosize Tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Gris-PEG Ultramicrosize Tablets.

Important safety information:

• Gris-PEG Ultramicrosize Tablets may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Gris-PEG Ultramicrosize Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Be sure to take Gris-PEG Ultramicrosize Tablets for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The fungus could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.


• Do not drink alcohol while you are taking Gris-PEG Ultramicrosize Tablets.


• Gris-PEG Ultramicrosize Tablets may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Gris-PEG Ultramicrosize Tablets. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.


• It is important to practice good hygiene during and after use to prevent reinfection.


• Hormonal birth control (eg, birth control pills) may not work as well while you are using Gris-PEG Ultramicrosize Tablets. To prevent pregnancy, use an extra form of birth control (eg, condoms).


• Lab tests, including complete blood cell counts, liver function, and kidney function, may be performed while you use Gris-PEG Ultramicrosize Tablets. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Gris-PEG Ultramicrosize Tablets should be used with extreme caution in CHILDREN younger than 3 years old; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: Do not take Gris-PEG Ultramicrosize Tablets if you are pregnant. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if Gris-PEG Ultramicrosize Tablets are found in breast milk. If you are or will be breast-feeding while you use Gris-PEG Ultramicrosize Tablets, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Gris-PEG Ultramicrosize Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Diarrhea; dizziness; headache; nausea; stomach upset; tiredness; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); butterfly-shaped rash on the face; confusion; fever, chills, or sore-throat; flu-like symptoms (eg, headache, joint pain); mental or mood changes; numbness, burning, or tingling of the hands or feet; red, swollen, blistered, or peeling skin; symptoms of liver problems (dark urine, pale stools, severe or persistent stomach pain, yellowing of the skin or eyes); white patches in the mouth.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Gris-PEG side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Gris-PEG Ultramicrosize Tablets:

Store Gris-PEG Ultramicrosize Tablets at room temperature, between 59 and 86 degrees F (15 and 30 degrees C), in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Gris-PEG Ultramicrosize Tablets out of the reach of children and away from pets.

General information:

• If you have any questions about Gris-PEG Ultramicrosize Tablets, please talk with your doctor, pharmacist, or other health care provider.


• Gris-PEG Ultramicrosize Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Gris-PEG Ultramicrosize Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Gris-PEG resources

• Gris-PEG Side Effects (in more detail)
• Gris-PEG Use in Pregnancy & Breastfeeding
• Drug Images
• Gris-PEG Drug Interactions
• Gris-PEG Support Group
• 3 Reviews for Gris-PEG - Add your own review/rating

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• Tinea Pedis

Imitrex Spray

Pronunciation: SOO-ma-TRIP-tan
Generic Name: Sumatriptan
Brand Name: Imitrex

Imitrex Spray is used for:

The treatment of migraine headaches with or without aura (eg, flashing lights, wavy lines, dark spots). It may also be used for other conditions as determined by your doctor.

Imitrex Spray is a serotonin 5-HT ₁ receptor agonist ("triptan"). It works by narrowing blood vessels in the brain, which helps to relieve migraines.

Do NOT use Imitrex Spray if:

• you are allergic to any ingredient in Imitrex Spray


• you have a history of ischemic heart disease (eg, angina, heart attack), coronary artery disease (CAD), other moderate to severe heart problems, brain blood vessel disease (eg, stroke, transient ischemic attack), or other blood vessel disease (eg, Raynaud syndrome, ischemic bowel disease)


• you have uncontrolled high blood pressure or severe liver problems


• you have certain types of migraines (eg, hemiplegic, basilar)


• you are taking or have taken a monamine oxidase inhibitor (MAOI) (eg, phenelzine) within the past 14 days


• you have used certain other migraine medicines within the past 24 hours (eg, an ergot derivative [eg, dihydroergotamine, methysergide], another serotonin 5-HT ₁ receptor agonist [eg, eletriptan, rizatriptan])


• you are taking sibutramine

Contact your doctor or health care provider right away if any of these apply to you.

Before using Imitrex Spray:

Some medical conditions may interact with Imitrex Spray. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have history of liver or kidney problems, seizures (eg epilepsy), heart problems, or other types of headaches (eg, cluster headaches)


• if you have shortness of breath, chest pain, or a history of high blood pressure, heart attack, stroke, high cholesterol, diabetes, or smoking


• if you are a woman who is past menopause


• if you are a man who is more than 40 years old


• if you are very overweight


• if a family member has had heart disease or a stroke

Some MEDICINES MAY INTERACT with Imitrex Spray. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine), serotonin norepinephrine reuptake inhibitors (SNRIs) (eg, duloxetine), orsibutramine because the risk of a serious side effect called serotonin syndrome may be increased. Symptoms of serotonin syndrome may include mental or mood changes, hallucinations, fast heartbeat, fever, loss of coordination, muscle spasms, increased sweating, nausea, vomiting, or diarrhea


• MAOIs (eg, phenelzine) because they may increase the risk of Imitrex Spray's side effects


• Ergot derivatives (eg, dihydroergotamine, methysergide) or other serotonin 5-HT ₁ receptor agonists (eg, eletriptan, rizatriptan) because the risk of their side effects may be increased by Imitrex Spray

This may not be a complete list of all interactions that may occur. Ask your health care provider if Imitrex Spray may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Imitrex Spray:

Use Imitrex Spray as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• An extra patient leaflet is available with Imitrex Spray. Talk to your pharmacist if you have questions about this information.


• A health care provider will teach you how to use Imitrex Spray. Be sure you understand how to use Imitrex Spray. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions.


• Imitrex Spray should be inhaled into the nose. Do not get it in your mouth or eyes. If you get it in your eyes, rinse right away with cool tap water.


• To use Imitrex Spray, remove the nasal spray unit from the plastic pack. Do not remove it until you are ready to use it.


• The unit contains only 1 spray. Do NOT test it before use.


• Sit down. Gently blow your nose to clear the nasal passages. Keep your head in an upright position, gently close 1 nostril with your index finger, and breathe out gently through the mouth. With your other hand, hold the container with your thumb at the bottom and your index and middle finger on either side of the nozzle. Insert the nozzle into your open nostril about ½ inch. Do not press the blue plunger yet.


• Keep your head upright and close your mouth. Gently take a breath through your nose and at the same time firmly press the blue plunger.


• Remove the nozzle from your nostril. Keep your head level for 10 to 20 seconds while gently breathing in through your nose and out through your mouth. Do NOT breathe in deeply.


• It is best to use a dose of Imitrex Spray as soon as you notice symptoms of a migraine attack.


• If your migraine symptoms go away and then come back, you may use a second dose as directed by your doctor. Wait at least 2 hours between doses.


• If your symptoms do not improve after the first dose, do not use a second dose for the same attack. Contact your doctor.


• Do not use more than the amount prescribed by your doctor in a 24-hour period or treat more than 4 headaches within 30 days without checking with your doctor.


• If you miss a dose of Imitrex Spray and you still have a headache, follow your doctor's dosing instructions. Contact your doctor if you are unsure of what to do if you miss a dose. Do not use Imitrex Spray more often than prescribed. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Imitrex Spray.

Important safety information:

• Imitrex Spray may cause drowsiness or dizziness. These effects may be worse if you take it with alcohol or certain medicines. Use Imitrex Spray with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Overuse of Imitrex Spray can cause your headache to become worse. Do NOT take more than the recommended dose or use more often than prescribed without checking with your doctor.


• Rarely, serious heart problems (eg, heart attack, irregular heartbeat) have been reported within a few hours of using Imitrex Spray. Contact your doctor at once if fast or irregular heartbeat; chest, jaw, or neck pain or numbness; numbness of an arm or leg; severe stomach pain, dizziness, or vomiting; fainting; or vision changes occur. Discuss any questions or concerns with your doctor.


• Serotonin syndrome is a possibly fatal syndrome that can be caused by Imitrex Spray. Your risk may be greater if you take Imitrex Spray with certain other medicines (eg, SSRIs, SNRIs). Symptoms may include agitation; confusion; hallucinations; coma; fever; fast or irregular heartbeat; tremor; excessive sweating; and nausea, vomiting, or diarrhea. Contact your doctor at once if you have any of these symptoms.


• Imitrex Spray should not be used to prevent or reduce the number of migraine headaches you have. If you have a headache that is different than your usual migraine headaches, check with your doctor before using Imitrex Spray.


• Lab tests, including heart function tests, may be performed while you use Imitrex Spray. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Imitrex Spray should not be used in the ELDERLY; the risk of serious side effects (eg, heart problems, high blood pressure) may be increased.


• Imitrex Spray should not be used in CHILDREN younger than 18 years old; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: It is not known if Imitrex Spray can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Imitrex Spray while you are pregnant. Imitrex Spray is found in breast milk. If you are or will be breast-feeding while you use Imitrex Spray, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Imitrex Spray:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Bad or unusual taste; burning, numbness, tingling, discharge, pain, or soreness of the nose, throat, or sinuses; dizziness; drowsiness; feeling of heaviness or pressure; mild, temporary flushing; nausea; sick feeling; tingling; tiredness; vomiting; warm/hot sensation.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody diarrhea; chest pain; confusion; fainting; fast or irregular heartbeat; fever; hallucinations; hearing problems; numbness or tingling of an arm or leg; one-sided weakness; pain, tightness, or pressure in the jaw, neck, or chest; seizures; severe headache, dizziness, or vomiting; severe or prolonged flushing; severe stomach pain; shortness of breath; speech changes; very cold or blue fingers or toes; vision changes or loss of vision; wheezing.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Imitrex side effects (in more detail)

If OVERDOSE is suspected:

Contact the US national poison control center (1-800-222-1222), your local poison control center, or emergency room immediately. Symptoms may include chest pain; seizures; slowed breathing; tremor.

Proper storage of Imitrex Spray:

Store Imitrex Spray between 36 and 86 degrees F (2 and 30 degrees C). Store away from heat, moisture, and light. Do not freeze. Do not store at temperatures above 86 degrees F (30 degrees C). Do not store in the bathroom. Keep Imitrex Spray in the case provided. Throw away expired medicine as directed by your doctor (the expiration date is printed on the treatment pack). Keep Imitrex Spray out of the reach of children and away from pets.

General information:

• If you have any questions about Imitrex Spray, please talk with your doctor, pharmacist, or other health care provider.


• Imitrex Spray is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is summary only. It does not contain all information about Imitrex Spray. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Imitrex resources

• Imitrex Side Effects (in more detail)
• Imitrex Use in Pregnancy & Breastfeeding
• Drug Images
• Imitrex Drug Interactions
• Imitrex Support Group
• 61 Reviews for Imitrex - Add your own review/rating

Compare Imitrex with other medications

• Cluster Headaches
• Cyclic Vomiting Syndrome
• Migraine
• New Daily Persistent Headache

magnesium amino acids chelate

Generic Name: magnesium amino acids chelate (mag NEE zee um a MEEN oh AS ids KEE late)

Brand Names: Chelated Magnesium, MG Plus Protein

What is magnesium amino acids chelate?

Magnesium is a naturally occurring mineral. Magnesium is important for many systems in the body especially the muscles and nerves.

Magnesium amino acids chelate is used as a supplement to maintain adequate magnesium in the body.

Magnesium amino acids chelate may also be used for purposes not listed in this medication guide.

What is the most important information I should know about magnesium amino acids chelate?

Before taking magnesium amino acids chelate, tell your doctor about all of your medical conditions, allergies, and any other medicines you use.

Tell your doctor if you are pregnant or breast-feeding. It is not known whether magnesium chloride could harm an unborn baby, or if it passes into breast milk and could harm a nursing baby. Your dose needs may be different while you are pregnant or breast-feeding.

Tell your doctor about all other medications you use, especially antibiotics, diuretics, or medication for osteoporosis or Paget's disease.

Tell your doctor if you have signs that your magnesium blood levels are too low, such as confusion, uneven heart rate, jerking muscle movements, and muscle weakness or limp feeling.

What should I discuss with my healthcare provider before taking magnesium amino acids chelate?

You should not use magnesium amino acids chelate if you are allergic to it, or if you have kidney disease.

To make sure you can safely take magnesium amino acids chelate, tell your doctor if you have any of these other conditions:

• 
  

  diabetes;

  
  


• 
  

  Crohn's disease, ulcerative colitis;

  
  


• 
  

  if you are malnourished; or

  
  


• 
  

  if you drink large amounts of alcohol.

  
  

FDA pregnancy category C. It is not known whether magnesium amino acids chelate will harm an unborn baby. Your dose needs may be different during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether magnesium amino acids chelate passes into breast milk or if it could harm a nursing baby. Your dose needs may be different while you are nursing. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take magnesium amino acids chelate?

Use this medication exactly as directed on the label, or as prescribed by your doctor. Do not use it in larger amounts or for longer than recommended.

Take this medication with a full glass of water.

Use magnesium amino acids chelate regularly to get the most benefit. Take the medicine at the same time each day.

To be sure this medication is helping your condition and not causing harmful effects, your blood may need to be tested on a regular basis. Your kidney function may also need to be tested. Do not miss any follow-up visits to your doctor.

Tell your doctor if you have signs that your magnesium blood levels are too low, such as confusion, uneven heart rate, jerking muscle movements, and muscle weakness or limp feeling.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include numbness or tingly feeling in your face, limp muscles, slow heartbeat, weak or shallow breathing, vomiting, or fainting.

What should I avoid while taking magnesium amino acids chelate?

Avoid using antacids or laxatives without your doctor's advice. Use only the specific type of antacid your doctor recommends. These medications may contain minerals and if you take certain products together you may get too much magnesium.

If you are taking a tetracycline antibiotic, avoid taking it within 2 hours before or 3 hours after you take magnesium amino acids chelate. Tetracycline antibiotics include doxycycline (Adoxa, Alodox, Avidoxy, Oraxyl, Doryx, Oracea, Vibramycin), minocycline (Dynacin, Minocin, Solodyn), or tetracycline (Ala-Tet, Brodspec, Panmycin, Sumycin, Tetracap).

Magnesium amino acids chelate side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; severe dizziness, difficult breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have severe or ongoing diarrhea.

• 
  

  depression, feeling tired or irritable;

  
  


• 
  

  muscle cramps;

  
  


• 
  

  severe or ongoing diarrhea.

  
  

Less serious side effects may include:

• 
  

  mild diarrhea;

  
  


• 
  

  nausea, stomach pain; or

  
  


• 
  

  upset stomach.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect magnesium amino acids chelate?

Tell your doctor about all other medicines you use, especially:

• 
  

  digoxin (Lanoxin, Lanoxicaps);

  
  


• 
  

  a diuretic (water pill);

  
  


• 
  

  an antibiotic such as ciprofloxacin (Cipro), levofloxacin (Levaquin), moxifloxacin (Avelox), norfloxacin (Noroxin), ofloxacin (Floxin), or penicillamine (Cuprimine, Depen); or

  
  


• 
  

  medicines for osteoporosis or Paget's disease, such as alendronate (Fosamax), etidronate (Didronel), ibandronate (Boniva), pamidronate (Aredia), risedronate (Actonel), tiludronate (Skelid), or zoledronic acid (Reclast, Zometa).

  
  

This list is not complete and other drugs may interact with magnesium amino acids chelate. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More magnesium amino acids chelate resources

• Magnesium amino acids chelate Drug Interactions
• Magnesium amino acids chelate Support Group
• 0 Reviews for Magnesium amino acids chelate - Add your own review/rating

Compare magnesium amino acids chelate with other medications

• Hypomagnesemia

Where can I get more information?

• Consult with a licensed healthcare professional before using any herbal/health supplement. Whether you are treated by a medical doctor or a practitioner trained in the use of natural medicines/supplements, make sure all your healthcare providers know about all of your medical conditions and treatments.

Promethazine with Codeine

Generic Name: codeine and promethazine (KOE deen and proe METH a zeen)

Brand Names: Codeine Phosphate-Promethazine HCl, Promethazine HCl and Codeine Phosphate, Promethazine with Codeine

What is Promethazine with Codeine (codeine and promethazine)?

Codeine is a narcotic. It is a pain reliever and a cough suppressant.

Promethazine is an antihistamine. It blocks the effects of the naturally occurring chemical histamine in your body.

The combination of codeine and promethazine is used to treat cold or allergy symptoms such as runny nose, sneezing, and cough.

Codeine and promethazine may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Promethazine with Codeine (codeine and promethazine)?

Tell your doctor about all of your medical conditions before you start taking this medication.

You should not use this medication if you are allergic to codeine or promethazine, or if you have asthma or other lung disease.

Codeine and promethazine may be habit-forming and should be used only by the person it was prescribed for. Keep the medication in a secure place where others cannot get to it. Do not give this medication to a child without medical advice. There are many other medicines that can cause interact with promethazine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

What should I discuss with my doctor before taking Promethazine with Codeine (codeine and promethazine)?

You should not use this medication if you are allergic to codeine or promethazine, or if you have high blood pressure, a blood vessel disorder, or asthma. Do not give this medication to a child without medical advice. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

To make sure you can safely take codeine and promethazine, tell your doctor if you have any of these other conditions:

• 
  

  epilepsy or other seizure disorder;

  
  


• 
  

  asthma, COPD, sleep apnea, or other breathing disorders;

  
  


• 
  

  glaucoma;

  
  


• 
  

  a stomach ulcer or digestive obstruction;

  
  


• 
  

  a weak immune system;

  
  


• 
  

  Addison's disease;

  
  


• 
  

  enlarged prostate, urination problems;

  
  


• 
  

  high or low blood pressure or heart disease;

  
  


• 
  

  liver or kidney disease;

  
  


• 
  

  underactive thyroid;

  
  


• 
  

  gallbladder disease; or

  
  


• 
  

  a head injury or brain tumor.

  
  

Codeine and promethazine may be habit forming and should be used only by the person it was prescribed for. Never share codeine and promethazine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it. FDA pregnancy category C. It is not known whether codeine and promethazine will harm an unborn baby. Codeine and promethazine may cause addiction or withdrawal symptoms in a newborn if the mother takes the medication during pregnancy. Tell your doctor if you are pregnant or plan to become pregnant while using codeine and promethazine. Codeine can pass into breast milk and may harm a nursing baby. The use of codeine by some nursing mothers may lead to life-threatening side effects in the baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

How should I take Promethazine with Codeine (codeine and promethazine)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Contact your doctor if your symptoms do not improve within a few days of using codeine and promethazine.

Store at room temperature away from moisture, heat, and light. Keep track of the amount of medicine used from each new bottle. Codeine and promethazine is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of this medication may be fatal.

Overdose symptoms include dizziness, extreme drowsiness, dry mouth, nausea, vomiting, cold and clammy skin, weak pulse, shallow breathing, fainting, seizure (convulsions), or breathing that stops.

What should I avoid while taking Promethazine with Codeine (codeine and promethazine)?

This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol can increase certain side effects of codeine and promethazine. Avoid exposure to sunlight or tanning beds. Codeine and promethazine can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Promethazine with Codeine (codeine and promethazine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Call your doctor at once if you have a serious side effect such as:

• 
  

  restless muscle movements in your eyes, tongue, jaw, or neck, tremor (uncontrolled shaking);

  
  


• 
  

  shallow breathing, slow heartbeat;

  
  


• 
  

  feeling like you might pass out;

  
  


• 
  

  jaundice (yellowing of the skin or eyes);

  
  


• 
  

  confusion, agitation, hallucinations, unusual thoughts or behavior;

  
  


• 
  

  seizure (convulsions);

  
  


• 
  

  urinating less than usual or not at all; or

  
  


• 
  

  very stiff (rigid) muscles, high fever, sweating, fast or uneven heartbeats, fainting.

  
  

Less serious side effects may include:

• 
  

  dizziness, drowsiness, sleepiness;

  
  


• 
  

  feeling restless, nervous, or anxious;

  
  


• 
  

  blurred vision, ringing in your ears;

  
  


• 
  

  constipation, mild nausea or vomiting;

  
  


• 
  

  warmth, redness, or tingly feeling under your skin;

  
  


• 
  

  sleep problems (insomnia);

  
  


• 
  

  increased sweating;

  
  


• 
  

  dry mouth; or

  
  


• 
  

  mild skin rash.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Promethazine with Codeine (codeine and promethazine)?

Tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, other pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by codeine and promethazine.

Many drugs can interact with codeine and promethazine. Below is just a partial list. Tell your doctor if you are using:

• 
  

  sedatives or anxiety medicines such as alprazolam (Xanax), diazepam (Valium), chlordiazepoxide (Librium), temazepam (Restoril), or triazolam (Halcion);

  
  


• 
  

  antidepressants such as amitriptyline (Elavil, Vanatrip, Limbitrol), doxepin (Sinequan), nortriptyline (Pamelor), fluoxetine (Prozac), sertraline (Zoloft), or paroxetine (Paxil);

  
  


• 
  

  narcotic pain medicines such as meperidine (Demerol), morphine (MS Contin, MSIR), propoxyphene (Darvon, Darvocet), hydrocodone (Lortab, Vicodin), oxycodone (Percocet, Percodan), fentanyl (Duragesic), codeine (Fiorinal, Fioricet, Tylenol #3);

  
  


• 
  

  phenobarbital (Luminal), amobarbital (Amytal) or secobarbital (Seconal);

  
  


• 
  

  an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate); or

  
  


• 
  

  atropine (Donnatal, and others), belladonna, clidinium (Quarzan), dicyclomine (Bentyl), glycopyrrolate (Robinul), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), methscopolamine (Pamine), and scopolamine (Transderm-Scop).

  
  

This list is not complete and other drugs may interact with codeine and promethazine. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Promethazine with Codeine resources

• Promethazine with Codeine Side Effects (in more detail)
• Promethazine with Codeine Use in Pregnancy & Breastfeeding
• Promethazine with Codeine Drug Interactions
• Promethazine with Codeine Support Group
• 1 Review for Promethazine with Codeine - Add your own review/rating

Compare Promethazine with Codeine with other medications

• Cough

Where can I get more information?

• Your pharmacist can provide more information about codeine and promethazine.

See also: Promethazine with Codeine side effects (in more detail)

Metrodin

Generic Name: urofollitropin (Intramuscular route, Subcutaneous route, Injection route)

ure-oh-FOL-li-troe-pin

Commonly used brand name(s)

In the U.S.

• Bravelle


• Fertinex

In Canada

• Fertinorm Hp


• Metrodin

Available Dosage Forms:

• Powder for Solution

Therapeutic Class: Female Reproductive Agent

Pharmacologic Class: Human Follicle Stimulating Hormone

Uses For Metrodin

Urofollitropin is a fertility drug that is identical to the hormone called follicle-stimulating hormone (FSH) that is produced naturally by the pituitary gland.

FSH is primarily responsible for stimulating growth of the ovarian follicle, which includes the developing egg, the cells surrounding the egg that produce the hormones needed to support a pregnancy, and the fluid around the egg. As the ovarian follicle grows, an increasing amount of the hormone estrogen is produced by the cells in the follicle and released into the bloodstream. Estrogen causes the endometrium (lining of the uterus) to thicken before ovulation occurs. The higher blood levels of estrogen will also provide a cue to the hypothalamus and pituitary gland to slow the production and release of FSH.

Another pituitary hormone, luteinizing hormone (LH), also helps to increase the amount of estrogen produced by the follicle cells. However, the main function of LH is to cause ovulation. The sharp rise in the blood level of LH that triggers ovulation is sometimes called the LH surge. After ovulation, the group of hormone-producing follicle cells become what is called the corpus luteum and will produce estrogen and large amounts of another hormone, progesterone. Progesterone causes the endometrium to mature so that it can support the egg after it is fertilized. If implantation of a fertilized egg does not occur, the levels of estrogen and progesterone decrease, the endometrium sloughs off, and menstruation occurs.

Urofollitropin is usually given in combination with human chorionic gonadotropin (hCG). The actions of hCG are almost identical to those of LH. It is given to simulate the natural LH surge. This results in predictable ovulation.

Urofollitropin is often used in women who have low levels of FSH and too-high levels of LH. Women with polycystic ovary syndrome usually have hormone levels such as this and are treated with urofollitropin to make up for the low amounts of FSH. Many women being treated with urofollitropin have already tried clomiphene (e.g., Serophene) and have not been able to conceive yet. Urofollitropin may also be used to cause the ovary to produce several follicles, which can then be harvested for use in gamete intrafallopian transfer (GIFT) or in vitro fertilization (IVF).

Urofollitropin is to be given only by or under the supervision of your doctor.

Before Using Metrodin

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pregnancy

	Pregnancy Category	Explanation
All Trimesters	X	Studies in animals or pregnant women have demonstrated positive evidence of fetal abnormalities. This drug should not be used in women who are or may become pregnant because the risk clearly outweighs any possible benefit.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

• Cyst on ovary—Urofollitropin can cause further growth of cysts on the ovary

• Unusual vaginal bleeding—Some irregular vaginal bleeding is a sign that the endometrium is growing too rapidly, possibly of endometrial cancer, or some hormone imbalances; the increases in estrogen production caused by urofollitropin can make these problems worse. If a hormonal imbalance is present, it should be treated before beginning menotropins therapy

Proper Use of urofollitropin

This section provides information on the proper use of a number of products that contain urofollitropin. It may not be specific to Metrodin. Please read with care.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For injection dosage form:
  
  • For becoming pregnant while having a condition called polycystic ovary syndrome:
    
    • Adults—75 Units injected under the skin or into a muscle once a day for seven or more days. Usually, another medicine called chorionic gonadotropin (hCG) will be given the day after the last dose. If needed, your doctor may then increase your dose of urofollitropin to 150 Units a day for another seven or more days. Higher doses may be prescribed by your doctor.
    
    
  
  
  • For becoming pregnant while using other pregnancy-promoting methods (assisted reproductive technology [ART]):
    
    • Adults—150 Units injected under the skin or into a muscle once a day. Your treatment will probably begin on Day 2 or Day 3 after your menstrual period begins. Usually, another medicine called chorionic gonadotropin (hCG) will be given the day after the last dose.
    
    
  
  

Precautions While Using Metrodin

It is very important that your doctor check your progress at regular visits to make sure that the medicine is working properly and to check for unwanted effects. Your doctor will likely want to monitor the development of the ovarian follicle(s) by measuring the amount of estrogen in your bloodstream and by checking the size of the follicle(s) with ultrasound examinations.

If your doctor has asked you to record your basal body temperature (BBT) daily, make sure that you do this every day. It is important that intercourse take place around the time of ovulation to give you the best chance of becoming pregnant.

Metrodin Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

More common

• Abdominal or pelvic pain


• bloating (mild)


• redness, pain, or swelling at the injection site

Less common or rare

• Abdominal or stomach pain (severe)


• bloating (moderate to severe)


• decreased amount of urine


• feeling of indigestion


• fever and chills


• nausea, vomiting, or diarrhea (continuing or severe)


• pelvic pain (severe)


• shortness of breath


• skin rash or hives


• swelling of lower legs


• weight gain (rapid)

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common or rare

• Breast tenderness


• diarrhea (mild)


• nausea


• vomiting

After you stop using this medicine, it may still produce some side effects that need attention. During this period of time, check with your doctor immediately if you notice the following side effects:

• Abdominal or stomach pain (severe)


• bloating (moderate to severe)


• decreased amount of urine


• feeling of indigestion


• nausea, vomiting, or diarrhea (continuing or severe)


• pelvic pain (severe)


• shortness of breath


• swelling of lower legs


• weight gain (rapid)

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Metrodin side effects (in more detail)

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More Metrodin resources

• Metrodin Side Effects (in more detail)
• Metrodin Use in Pregnancy & Breastfeeding
• Metrodin Drug Interactions
• Metrodin Support Group
• 0 Reviews for Metrodin - Add your own review/rating

• Urofollitropin Professional Patient Advice (Wolters Kluwer)


• Bravelle Prescribing Information (FDA)


• Bravelle Concise Consumer Information (Cerner Multum)


• Bravelle MedFacts Consumer Leaflet (Wolters Kluwer)


• Fertinex MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Metrodin with other medications

• Female Infertility
• Follicle Stimulation

Junior Meltus Dry Coughs with Congestion

1. Name Of The Medicinal Product

Junior Meltus Dry Coughs with Congestion

2. Qualitative And Quantitative Composition

Dextromethorphan Hydrobromide BP 3.5mg/5ml; Pseudoephedrine Hydrochloride BP 10.0mg/5ml.

3. Pharmaceutical Form

Oral solution.

4. Clinical Particulars

4.1 Therapeutic Indications

An oral solution for the symptomatic relief of unproductive coughs accompanied by congestion of the upper respiratory tract.

4.2 Posology And Method Of Administration

To be given four times a day. Do not repeat dosage more frequently than every four hours. Children 6-12 years: Two 5ml spoonfuls. Children 2-5 years: One 5ml spoonful. Adults, the elderly and children over 12 years are recommended to take Adult Meltus Dry Coughs with Congestion. Not to be given to children under two years of age.

4.3 Contraindications

Junior Meltus Dry Coughs with Congestion is contraindicated in patients with a known hypersensitivity to pseudoephedrine or dextromethorphan. Contraindicated in persons under treatment with monoamine oxidase inhibitors or within 2 weeks of stopping such treatment. Contraindicated in patients with severe hypertension or severe coronary artery disease. Junior Meltus Dry Coughs with Congestion should not be administered to patients where the cough is associated with asthma or where the cough is accompanied by excessive secretions. Dextromethorphan, in common with other centrally acting antitussive agents, should not be given to patients in or at risk of developing respiratory failure. Although pseudoephedrine has virtually no pressor effect in patients with normal blood pressure, Junior Meltus Dry Coughs with Congestion should be used with caution in patients taking antihypertensive agents, tricyclic antidepressants, other sympathomimetic agents, such as decongestants, appetite suppressants and amphetamine-like psychostimulants. The effects of a single dose of Junior Meltus Dry Coughs with Congestion on the blood pressure of these patients should be observed before recommending repeated or unsupervised treatment. As with other sympathomimetic agents, caution should be exercised in patients with uncontrolled diabetes, hyperthyroidism, elevated intraocular pressure and prostatic enlargement.

4.4 Special Warnings And Precautions For Use

Keep out of the reach of children. Do not exceed the stated dose. If currently taking any other medicine, consult with a doctor or pharmacist before taking this product. If symptoms persist, consult your doctor.

4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction

Concomitant use of Junior Meltus Dry Coughs with Congestion with sympathomimetic agents such as decongestants, tricyclic antidepressants, appetite suppressants and amphetamine-like psychostimulants, or with monoamine oxidase inhibitors which interfere with the catabolism of sympathomimetic amines, may occasionally cause a rise in blood pressure. Because of its pseudoephedrine content, the effect of antihypertensive agents which modify sympathetic activity may be partially reversed by Junior Meltus Dry Coughs with Congestion. The antibacterial agent, furazolidine, is known to cause a dose-related inhibition of monoamine oxidase and although there are no reports of a hypertensive crisis having occurred, it should not be administered concurrently with Junior Meltus Dry Coughs with Congestion. The product may potentiate the effects of alcohol and other central nervous system depressants.

4.6 Pregnancy And Lactation

Not applicable.

4.7 Effects On Ability To Drive And Use Machines

Not applicable.

4.8 Undesirable Effects

In some patients, pseudoephedrine may occasionally cause insomnia. Rarely, sleep disturbance and hallucinations have been reported. Fixed drug eruption due to pseudoephedrine, taking the form of erythematous nummular patches, has been reported as a rare event. Side-effects attributed to dextromethorphan are uncommon; occasionally dizziness, nausea, vomiting or gastrointestinal disturbance may occur.

4.9 Overdose

The effects of acute toxicity from Junior Meltus Dry Coughs with Congestion may include nystagmus, hypertension, irritability, restlessness, tremor, palpitations, visual and auditory hallucinations, convulsions, respiratory depression, difficulty with micturition, nausea and vomiting. Gastric lavage and supportive measures for respiration and circulation should be performed if indicated. Convulsions should be controlled with an anticonvulsant. Catheterisation of the bladder may be necessary. If desired, the elimination of pseudoephedrine can be accelerated by acid diuresis or by dialysis. Naloxone has been used successfully as a specific antagonist to dextromethorphan toxicity in a child.

5. Pharmacological Properties

5.1 Pharmacodynamic Properties

Cough suppressant; decongestant.

5.2 Pharmacokinetic Properties

Not applicable.

5.3 Preclinical Safety Data

None stated.

6. Pharmaceutical Particulars

6.1 List Of Excipients

Sorbitol Syrup (Non Crystallising) BP; Menthol BP; Chloroform BP; Loganberry Flavour 500195E; Methylhydroxybenzoate BP; Propylhydroxybenzoate BP; Alcohol 96% BP; Glycerin BP; Sodium Saccharin BP; Sodium Cyclamate 1968 BP; Carmellose Sodium BP; Water.

6.2 Incompatibilities

None known.

6.3 Shelf Life

36 months unopened.

6.4 Special Precautions For Storage

Store below 25^oC and avoid prolonged storage at 5^oC or below.

6.5 Nature And Contents Of Container

Amber glass bottle with tamper evident cap with fitted polycone liner packed in an outer carton. Bottle contains 100ml of product.

6.6 Special Precautions For Disposal And Other Handling

None stated.

7. Marketing Authorisation Holder

Cupal Ltd. Venus, 1 Old Park Lane, Trafford Park, Manchester, M41 7HA.

8. Marketing Authorisation Number(S)

PL 0338/0070.

9. Date Of First Authorisation/Renewal Of The Authorisation

11^th October 1991 / 12^th June 2003

10. Date Of Revision Of The Text

April 2006

CP Dec DM

Generic Name: chlorpheniramine, dextromethorphan, and phenylephrine (klor feh NEER a meen, dex troe meh THOR fan, and feh nill EH frin)

Brand Names: Alka-Seltzer Plus Cold and Cough, C-Phen DM, C-Phen DM Drops, Cardec DM, Cardec DM Drops, Ceron-DM, Ceron-DM Drops, Cerose DM, Corfen-DM, CP Dec DM, CP Dec-DM Drops, De-Chlor DM, De-Chlor DR, Dec-Chlorphen DM, Dex PC, DM-PE-Chlor, Donatussin DM Drops, Ed A-Hist DM, HistadecDM, Maxiphen ADT, Mintuss DR, Nasohist-DM, Neo DM Drops, Nohist-DMX, Norel DM, P Chlor DM, PD-Cof, PD-Cof Drops, Poly-Tussin DM, Quartuss DM, Reme Tussin DM, Rondec-DM, Rondec-DM Drops, Rondex-DM, Rondex-DM Drops, Sildec-PE DM, Sildec-PE DM Drops, Tri-Vent DPC, Trital DM, Tussplex DM, Zotex-12D

What is CP Dec DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

Chlorpheniramine is an antihistamine that reduces the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Dextromethorphan is a cough suppressant. It affects the signals in the brain that trigger cough reflex.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Chlorpheniramine, dextromethorphan, and phenylephrine is used to treat sneezing, cough, runny or stuffy nose, itchy or watery eyes, hives, skin rash, itching, and other symptoms of allergies and the common cold.

Dextromethorphan will not treat a cough that is caused by smoking, asthma, or emphysema.

Chlorpheniramine, dextromethorphan, and phenylephrine may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about CP Dec DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body. Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, or cough suppressant. Chlorpheniramine, dextromethorphan, and phenylephrine can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of this medication.

What should I discuss with my healthcare provider before taking CP Dec DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

Do not use a cough or cold medicine if you have used an MAO inhibitor such as isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam), or tranylcypromine (Parnate) within the past 14 days. Serious, life-threatening side effects can occur if you take cough or cold medicine before the MAO inhibitor has cleared from your body.

Before taking this medication, tell your doctor if you are allergic to chlorpheniramine, dextromethorphan, or phenylephrine, or if you have:

• kidney disease;


• liver disease;


• 
  

  diabetes;

  
  


• 
  

  glaucoma;

  
  


• 
  

  heart disease or high blood pressure;

  
  


• 
  

  diabetes;

  
  


• 
  

  a thyroid disorder;

  
  


• 
  

  a stomach ulcer or a stomach obstruction,

  
  


• 
  

  emphysema or chronic bronchitis; or

  
  


• 
  

  an enlarged prostate or urination problems.

  
  

If you have any of these conditions, you may need a dose adjustment or special tests to safely take this medication.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Chlorpheniramine, dextromethorphan, and phenylephrine can pass into breast milk and may harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby.

Artificially-sweetened liquid forms of cough-and-cold medications may contain phenylalanine. This would be important to know if you have phenylketonuria (PKU). Check the ingredients and warnings on the medication label if you are concerned about phenylalanine.

How should I take CP Dec DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

Use this medication exactly as directed on the label or as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor.

Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children. Take this medicine with a full glass of water. If you use the effervescent tablet, drop the tablet in 8 ounces of water and allow it to dissolve completely. Stir this mixture and drink all of it right away. To make sure you get the entire dose, add a little more water to the same glass, swirl gently and drink right away.

Measure the liquid form of this medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one.

Take this medicine with food or milk if it upsets your stomach.

This medication can cause you to have unusual results with allergy skin tests. Tell any doctor who treats you that you are taking an antihistamine.

Talk with your doctor if your symptoms do not improve after 7 days of treatment, or if you have a fever with a headache, cough, or skin rash.

If you need to have any type of surgery, tell the surgeon ahead of time if you have taken a cold medicine within the past few days.

Store the medication at room temperature away from moisture and heat.

What happens if I miss a dose?

Since cough or cold medicine is usually taken only as needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the medicine at your next regularly scheduled time. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include feeling restless or nervous, nausea, vomiting, stomach pain, dizziness, drowsiness, dry mouth, warmth or tingly feeling, or seizure (convulsions).

What should I avoid while taking CP Dec DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It can increase some of the side effects of this medication. Before taking this medication, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by this medication.

Avoid taking diet pills, caffeine pills, or other stimulants (such as ADHD medications) without your doctor's advice. Taking a stimulant together with a decongestant can increase your risk of unpleasant side effects.

Do not use any other over-the-counter cough, cold, allergy, or sleep medication without first asking your doctor or pharmacist. Antihistamines, decongestants, and cough suppressants are contained in many medicines available over the counter. If you take certain products together you may accidentally take too much of one or more types of medicine. Read the label of any other medicine you are using to see if it contains an antihistamine, decongestant, or cough suppressant.

CP Dec DM (chlorpheniramine, dextromethorphan, and phenylephrine) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have any of these serious side effects:

• 
  

  fast, pounding, or uneven heartbeat;

  
  


• 
  

  confusion, hallucinations, unusual thoughts or behavior;

  
  


• 
  

  severe dizziness, anxiety, restless feeling, or nervousness;

  
  


• 
  

  increased blood pressure (severe headache, blurred vision, trouble concentrating, chest pain, numbness, seizure);

  
  


• 
  

  confusion, hallucinations;

  
  


• 
  

  slow, shallow breathing;

  
  


• 
  

  urinating less than usual or not at all;

  
  


• 
  

  easy bruising or bleeding, unusual weakness, fever, chills, body aches, flu symptoms; or

  
  


• 
  

  nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

  
  

Less serious side effects may include:

• 
  

  blurred vision;

  
  


• 
  

  dry mouth;

  
  


• 
  

  nausea, stomach pain, constipation;

  
  


• 
  

  mild loss of appetite, stomach upset;

  
  


• 
  

  warmth, tingling, or redness under your skin;

  
  


• 
  

  feeling excited or restless;

  
  


• 
  

  sleep problems (insomnia);

  
  


• 
  

  restless or excitability (especially in children);

  
  


• 
  

  skin rash or itching;

  
  


• 
  

  dizziness, drowsiness;

  
  


• 
  

  problems with memory or concentration; or

  
  


• 
  

  ringing in your ears.

  
  

This is not a complete list of side effects and others may occur. Tell your doctor about any unusual or bothersome side effect. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect CP Dec DM (chlorpheniramine, dextromethorphan, and phenylephrine)?

Before taking this medication, tell your doctor if you are using any of the following drugs:

• 
  

  an antidepressant;

  
  


• 
  

  a diuretic (water pill);

  
  


• 
  

  medication to treat irritable bowel syndrome;

  
  


• 
  

  celecoxib (Celebrex);

  
  


• 
  

  cinacalcet (Sensipar);

  
  


• 
  

  imatinib (Gleevec);

  
  


• 
  

  quinidine (Quinaglute, Quinidex);

  
  


• 
  

  ranolazine (Ranexa)

  
  


• 
  

  ritonavir (Norvir);

  
  


• 
  

  sibutramine (Meridia);

  
  


• 
  

  terbinafine (Lamisil);

  
  


• 
  

  medicines to treat high blood pressure;

  
  


• 
  

  aspirin or salicylates (such as Disalcid, Doan's Pills, Dolobid, Salflex, Tricosal, and others);

  
  


• 
  

  bladder or urinary medications such as darifenacin (Enablex), oxybutynin (Ditropan, Oxytrol) or tolterodine (Detrol); or

  
  


• 
  

  a beta-blocker such as atenolol (Tenormin), carteolol (Cartrol), metoprolol (Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal), sotalol (Betapace), timolol (Blocadren), and others.

  
  

This list is not complete and there may be other drugs that can interact with chlorpheniramine, dextromethorphan, and phenylephrine. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More CP Dec DM resources

• CP Dec DM Side Effects (in more detail)
• CP Dec DM Use in Pregnancy & Breastfeeding
• CP Dec DM Drug Interactions
• CP Dec DM Support Group
• 0 Reviews for CP Dec DM - Add your own review/rating

• Bronkids Drops MedFacts Consumer Leaflet (Wolters Kluwer)


• Cardec DM Elixir MedFacts Consumer Leaflet (Wolters Kluwer)


• Ceron-DM Liquid MedFacts Consumer Leaflet (Wolters Kluwer)


• Maxiphen ADT MedFacts Consumer Leaflet (Wolters Kluwer)


• Quartuss DM Prescribing Information (FDA)


• Trital DM Prescribing Information (FDA)

Compare CP Dec DM with other medications

• Cough and Nasal Congestion

Where can I get more information?

• Your pharmacist can provide more information about chlorpheniramine, dextromethorphan, and phenylephrine.

See also: CP Dec DM side effects (in more detail)